Apparent failure of ultrasonography to detect adult worms of Brugia malayi.
Identifieur interne : 00A284 ( Main/Exploration ); précédent : 00A283; suivant : 00A285Apparent failure of ultrasonography to detect adult worms of Brugia malayi.
Auteurs : R K Shenoy [Inde] ; A. John ; S. Hameed ; T K Suma ; V. KumaraswamiSource :
- Annals of tropical medicine and parasitology [ 0003-4983 ] ; 2000.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Brugia malayi (isolement et purification), Filariose lymphatique (imagerie diagnostique), Filariose lymphatique (parasitologie), Humains, Mâle, Résultat thérapeutique, Scrotum (imagerie diagnostique), Wuchereria bancrofti (isolement et purification), Échographie.
- MESH :
- imagerie diagnostique : Filariose lymphatique, Scrotum.
- isolement et purification : Brugia malayi, Wuchereria bancrofti.
- parasitologie : Filariose lymphatique.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Humains, Mâle, Résultat thérapeutique, Échographie.
English descriptors
- KwdEn :
- MESH :
- diagnostic imaging : Elephantiasis, Filarial, Scrotum.
- isolation & purification : Brugia malayi, Wuchereria bancrofti.
- parasitology : Elephantiasis, Filarial.
- Adolescent, Adult, Animals, Humans, Male, Middle Aged, Treatment Outcome, Ultrasonography.
Abstract
Adult worms of Wuchereria bancrofti, or rather their characteristic movements (the 'filarial dance'), can now be detected in the scrotal lymphatics of microfilaraemic males, using ultrasonography. This ability has been used to delineate the lymphatic pathology of bancroftian filariasis, guide the surgical removal of the adult worms and, most importantly, assess the macrofilaricidal effects of antifilarial drugs. In the present study, the first report of the use of ultrasonography in brugian filariasis, 22 men (aged 18-62 years) with 60-2972 (median = 370) Brugia malayi microfilariae/ml blood were subjected to ultrasonography using a linear, 7.5-MHz probe. In addition, four other men (aged 19-35 years), with W. bancrofti microfilaraemia [28-524 (median = 234) microfilariae/ml], were similarly examined. Adult worms were not detectable in any of the patients with B. malayi parasitaemia but were detected in the scrotal lymphatics of two of the four individuals with W. bancrofti infection. The reasons for the failure to detect adult B. malayi and the limitations of ultrasound as a screening tool are examined. The results highlight the differences between the two species that cause most lymphatic filariasis and the need for rapid development of tools that can be used for the control of brugian lymphatic filariasis.
PubMed: 10723526
Affiliations:
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Hameed</name></author><author><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></author><author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. 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Medical College Hospital, Alappuzha, India. rkshenoy@md3.vsnl.net.in</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Filariasis Chemotherapy Unit, T.D. Medical College Hospital, Alappuzha</wicri:regionArea><wicri:noRegion>Alappuzha</wicri:noRegion></affiliation></author><author><name sortKey="John, A" sort="John, A" uniqKey="John A" first="A" last="John">A. John</name></author><author><name sortKey="Hameed, S" sort="Hameed, S" uniqKey="Hameed S" first="S" last="Hameed">S. Hameed</name></author><author><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></author><author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name></author></analytic><series><title level="j">Annals of tropical medicine and parasitology</title><idno type="ISSN">0003-4983</idno><imprint><date when="2000" type="published">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Brugia malayi (isolation & purification)</term><term>Elephantiasis, Filarial (diagnostic imaging)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Scrotum (diagnostic imaging)</term><term>Treatment Outcome</term><term>Ultrasonography</term><term>Wuchereria bancrofti (isolation & purification)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Brugia malayi (isolement et purification)</term><term>Filariose lymphatique (imagerie diagnostique)</term><term>Filariose lymphatique (parasitologie)</term><term>Humains</term><term>Mâle</term><term>Résultat thérapeutique</term><term>Scrotum (imagerie diagnostique)</term><term>Wuchereria bancrofti (isolement et purification)</term><term>Échographie</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Scrotum</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Filariose lymphatique</term><term>Scrotum</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Brugia malayi</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Brugia malayi</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term><term>Ultrasonography</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Humains</term><term>Mâle</term><term>Résultat thérapeutique</term><term>Échographie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Adult worms of Wuchereria bancrofti, or rather their characteristic movements (the 'filarial dance'), can now be detected in the scrotal lymphatics of microfilaraemic males, using ultrasonography. This ability has been used to delineate the lymphatic pathology of bancroftian filariasis, guide the surgical removal of the adult worms and, most importantly, assess the macrofilaricidal effects of antifilarial drugs. In the present study, the first report of the use of ultrasonography in brugian filariasis, 22 men (aged 18-62 years) with 60-2972 (median = 370) Brugia malayi microfilariae/ml blood were subjected to ultrasonography using a linear, 7.5-MHz probe. In addition, four other men (aged 19-35 years), with W. bancrofti microfilaraemia [28-524 (median = 234) microfilariae/ml], were similarly examined. Adult worms were not detectable in any of the patients with B. malayi parasitaemia but were detected in the scrotal lymphatics of two of the four individuals with W. bancrofti infection. The reasons for the failure to detect adult B. malayi and the limitations of ultrasound as a screening tool are examined. The results highlight the differences between the two species that cause most lymphatic filariasis and the need for rapid development of tools that can be used for the control of brugian lymphatic filariasis.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Hameed, S" sort="Hameed, S" uniqKey="Hameed S" first="S" last="Hameed">S. Hameed</name><name sortKey="John, A" sort="John, A" uniqKey="John A" first="A" last="John">A. John</name><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></noCountry><country name="Inde"><noRegion><name sortKey="Shenoy, R K" sort="Shenoy, R K" uniqKey="Shenoy R" first="R K" last="Shenoy">R K Shenoy</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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